It is impossible for that man to despair who remembers that his Helper is omnipotent.

Despair depends on believing that the situation is closed and that nothing further can arrive. Anyone who holds that there is help beyond their own strength has a door left open, and that changes what the same hard facts feel like. None of this is a rebuke to anyone who cannot summon that belief, and low spirits are not a failure of it.

When things look closed, test the assumption rather than the feeling: write down what you are certain cannot change, and mark which items you actually know. Then ask one person for help, since help arriving from outside is the part despair never accounts for.