Nothing puzzles me more than the time and space; and yet nothing troubles me less.

Some questions are genuinely unanswerable and also genuinely harmless. You can find the size of things baffling, hold no explanation at all for why there is anything rather than nothing, and still sleep soundly. Curiosity and anxiety are separate states, and a puzzle only turns into a burden when you decide you were supposed to have solved it.

Notice which of your open questions actually press on you and which you have merely filed as unfinished business. Let one of the second kind stay open on purpose this week. You can stay interested in something without needing it settled.